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With a move to the countryside already testing the limits of a couple's relationship, a supernatural encounter begins an extreme transformation of their love, their lives, and their flesh.

Trying to leave their troubled lives behind, twin brothers return to their hometown to start again, only to discover that an even greater evil is waiting to welcome them back.

In Knockemstiff, Ohio and its neighboring backwoods, sinister characters converge around young Arvin Russell as he fights the evil forces that threaten him and his family.